Government Aided Pharmacy College Permanently Affiliated To University Of Mumbai, Approved By AICTE DTE And PCI, NBA Accreditation For 2008-2013,

Only Pharmacy Institute in INDIA rated as Best Industry Linked under Mentor category by AICTE-CII

MISSION

To educate and train students in the knowledge and practice of pharmaceutical sciences and to contribute to improvement of health of the society, through education and research programs.

VISION

To be a leader in Pharmacy Education, Pharmacy Training, and Research in Pharmaceutical Sciences.

Department of Pharmacology and Toxicology Departments

Name of the Faculty: Dr. Madhusudan Natvarlal Saraf

Designation: Principal and Professor of Pharmacology

Email: saraf@bcpindia.org

Teaching Fields: Pharmacology and toxicology





Educational Qualifications:

Sr no. Degree University Year of Passing
1) Ph. D. (Tech) Mumbai University 1985
2) M. Pharm. Mumbai University 1977
3) B. Pharm. Mumbai University 1973

Recent Publications: (Best Five in last five years)

Sr no. Award/Fellowship Year of Receipt
1) Recipient of Scholarship by Drew University U.S.A (1999). 1999
2) Member of Ad-hoc board in Pharmacy, University of Mumbai. (1993-). 1993
3) Recipient of Development Fellowship from Association of Commonwealth Universities London, (1989). 1989
4) Recipient of Scholarship from University Grant Commission to visit Russia Moscow, (1987) Leningrad, Novosibisk. . 1987
5) Recipient of National Associateship and visiting Associateship from University Grants Commission (1985-86) . 1985

Awards and Fellowships:

Sr no. Paper Title Journal / Year / Vol / Page
1) Investigation into the mechanism of action of essential oil of pistacia integerrima for its antiasthmatic activity Journal of ethnopharmacology, 2014, 153, 541-551.
2) Bodhankar; Estimation of the long-term cardiovascular events using ukpds risk engine in metabolic syndrome patients Indian journal of pharmaceutical sciences, 2014, 76, 174-178.
3) Evaluation of effect of murraya koenigii on restraint stress induced perturbations Research Journal of Pharmacology and Pharmacodynamics, 2011, 3, 184-191.
4) Exacerbation of alcohol-induced oxidative stress in rats by polyunsaturated fatty acids and iron load Indian journal of pharmaceutical sciences, 2011, 73, 152-158.
5) Recipient of National Associateship and visiting Associateship from University Grants Commission (1985-86) . 1985
5) Antioxidant activity of eclipta alba l. In normal rat liver Iranian Journal of Pharmacology & Therapeutics (IJPT), 2010, 9, 103-105.

Recent Patents:(ALL)

Sr no. Patent Title Patent Number
1) 6-Methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3, 4-tetrahydropyrimidin-2-one derivatives as antitubercular agents WO2011151701A1
2) 6-Methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3, 4-tetrahydropyrimidin-2-one derivatives as antitubercular agents CN102971301A

Recent Presentations: (Best Five in last five years)

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) SARTANS, AT1 receptor and nociception: connecting the missing links IASP NeupSIG, 4th International Congress on Neuropathic Pain - May 23-26, 2013, Toronto, Canada
2) Biochemical and cellular correlates of embelin against bacterial endotoxin induced airway inflammation Front. Immunol. Conference 15th International Congress of Immunology (ICI) 22 Aug - 27 Aug, 2013 Milan, Italy
3) Evaluation of Antisickling Activity of T-Ayu-HM Pre in vitro 41st Annual Convention of Sickle cell Disease Association of America September 24th - 27th 2013 Baltimore MD, USA.
4) Antisickling Activity of a Natural Anthraquinone (Aloin) in vitro 55th ASH Annual Meeting and Exposition December 7th - 10th 2013 New Orleans, LA.
5) Antiprotenuric and nephroprotective effects of methanolic extract of Butea monosperma (Lam.) in doxorubicin induced nephrotic syndrome 5th Global Summit on Medicinal and Aromatic Plants (GOSMAP-5), December 8 -12, 2013, Miri, Malaysia

Collaborations: (in current year)

Sr no. Title Industry/institute
1) Confidential Haffkin institute
2) Confidential Homi Bhaha Institute
3) Confidential PCP(BVDU pune)

Research Area and interest:

Immunopharmacology, pharmacology of medicinal plants, toxicolo

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Name of the Faculty: Dr. (Mrs.) Anuradha S. Majumdar

Designation: Asst. Professor of Pharmacology

Email: anuradha.majumdar@gmail.com









Educational Qualifications:

Sr no. Degree University Year of Passing
1) B. Pharm Nagpur University 1994
2) M. Pharm (Pharmacology) Nagpur University 1996
3) Ph. D. (Tech) (Pharmacology) University of Mumbai 2006

Awards and Fellowships:

Sr no. Award/Fellowship Year of Receipt
1) Member of the senate of the University of Mumbai 2010-2015
2) Gold medal in Avishkar 2014 (Maharashtra state level), UG level in Jalgaon, Maharashtra for the paper “Quercetin rich extract from onion peel and its antioxidant activity” 2014
3) Consolation prize in Avishkar 2012 (Maharashtra state level), University of Mumbai, Scientific Competition on the paper “Resveratrol: Potential to combat against corticosteroid insensitivity in COPD” 2012
4) Paper entitled "Exacerbation of alcohol- induced oxidative stress in rats by polyunsaturated fatty acids and iron load" authored by ShilpaPatere, A. S. Majumdar and M.N. Saraf published in the Indian Journal of Pharmaceutical Sciences, 2011; 73 (2) 152-158, has been adjudged as the best paper in the field of Pharmacology & Clinical Pharmacy for Prof M. L. Khorana Memorial Prize of Indian Pharmaceutical Association for the year 2011 2011
5) Received Shri Salebhai A. Vali Memorial gold medal for standing first in order of merit in M. Pharm in Nagpur University 1996

Recent Publications:

Sr no. Paper Title Journal / Year / Vol / Page
1) “Potential of ozonated sesame oil to augment wound healing in rats” Indian Journal of Pharmaceutical Sciences; January - February 2014,Volume 76.1, Page no.87-92
2) "Resveratrol and melatonin abated ovariectomy and fructose diet induced obesity and metabolic alterations in female rats" Menopause ;August 2014, Volume 21.8, Page no. 1-10
3) “New evidences of neurotoxicity of aroclor 1254 in mice brain: Potential of coenzyme Q10 in abating the detrimental outcomes” Environmental Health and Toxicology; March 2014, Volume 29, Page no.1-7
4) “Somnipathy (Sleep Disorder)– A Brief Review” The Pharma Review; July-August 2013, Page no.119-124
5) "Resveratrol attenuated smokeless tobacco induced vascular and metabolic complications in ovariectomized rats” Menopause; August 2013, 20.8, Page no.869-876

Recent Patents:(ALL)

Sr no. Patent Title Patent Number
1) “A Novel Pharmaceutical Composition of topical Methotrexate in chronic inflammatory condition” Inventors: Dr.AnuradhaMajumdar and Ms. Norma Andrades 251524 (Indian Patent)

Recent Presentations: (Best Five in last five years)

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) “Vitamin D deficiency and diabetes: Perceptions of pharmacists and physicians” ISPOR 5th Asia-Pacific Conference, 2-4 September 2012, Taipei, Taiwan
2) “Resveratrol: Potential application in Combat against corticosteroid insensitivity in COPD” IPSCON 2012, 45th annual conference of Indian Pharmacological Society and International Conference on “Navigating Pharmacology towards safe and effective therapy” from Jan 05-07, 2013, Nagpur
3) “Sub anorectic dose of sibutramine in combination with melatonin results in attenuation of obesity in diet induced obese rats” 19th European Congress on obesity, May 9-12, 2012, Lyon, France
4) “Role of resveratrol in attenuation of smokeless tobacco induced vascular and metabolic dysfunction” 12th International Congress of Ethnopharmacology”, Traditional medicine and globalization- The future of ancient systems of medicine, February 17-19, 2012, Kolkata
5) “Lidocaine, rimonabant, WIN 55,212-2 and capsazepine attenuate massive lung inflammation induced by the intratracheal administration of cigarette smoke extract in rats” South Asian Chapter of American College of Clinical Pharmacology, Fifth International Annual Conference, Clinical Pharmacology-Discovery, development and beyond, 27th and 28th August 2011, Mumbai

Collaborations: (in current year)

Sr no. Title Industry/institute
1) Targeting deacetylases and Methyl transferases to improve outcomes after allogeneic bone marrow transplantation in chemo-conditioning based murine model of acute graft versus host disease Clinical Pharmacology lab (KS-102),Advanced Centre for Treatment, Research & Education in cancer (ACTREC),TMC,Kharghar,Navi-Mumbai
2) Targeting the life - threatening complications (HVOD.GVHD) associated with allogeneic Haematopoietic Stem Cell Transplantation (allo HSCT). Clinical Pharmacology lab (KS-102),Advanced Centre for Treatment, Research & Education in cancer (ACTREC),TMC,Kharghar,Navi-Mumbai
3) Radiotracer based bio-distribution studies of a novel nanocarrier based transdermal delivery system for rheumatoid arthritis Board of Radiation and Isotope Technology, Vashi, Navi-Mumbai

Consultancy Services: (in last five years)

Sr no. Title Industry/institute
1) Drug evaluation Shreya Life Sciences, Mumbai
2) Preclinical R& D Yasham P2D, Mumbai
3) Product evaluation Marico Ltd., Mumbai

Research Area and interest:

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Evaluation of photosensitivity of drugs & formulations and strategies for improving photo stability and minimizing photo toxicity.

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Research on inflammatory disorders, vascular endothelial dysfunction, cardiovascular and metabolic diseases.

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Research on SIRT modulators in smokeless tobacco related exacerbation of cardiovascular and metabolic complications in estrogen deficient states.

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Research on role of receptors and targets in cigarette smoke induced neurogenic pain and inflammation in lungs.

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Evaluation of herbals and synthetic molecules for various pharmacological activities.

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Toxicological testing, viz., acute, sub-acute, chronic toxicity, Dermal toxicity, Neurotoxicity, Cardiotoxicity, Endocrine disruption, Neuronal toxicity, Vascular toxicity etc. using various animal models (Rat, Mice, Guinea pig & Rabbits).

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Preclinical pharmacokinetic studies.

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Behavioural pharmacology

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Zebra fish as a model for investigating developmental toxicity, reproductive toxicity & whole body apoptosis.

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Effect of heavy metals and environmental toxicants on CNS.

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Haematopoietic Stem Cell Transplantation and complications associated with it (Graft Versus Host Disease& Hepatic Veno Occlusive Disease).

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In- vitro screening of anti-cancer drug molecule for its cytotoxicity (MTT assay, SRB assay), live cell as well as fixed cell imaging for entrapment of anti-cancer drug molecule inside the cells.

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Pre-clinical murine model development for in- vivo pre-clinical evaluation of anti- cancer drug molecule.

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Intracerebroventricular drug delivery using stereotaxic apparatus and Cerebrospinal fluid (CSF) tapping/aspiration for biomarker and drug/metabolite analysis.


Expertise and instrumental/research facilities you can provide to interested parties:

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Radio-immuno assay lab authorised by Atomic Energy Regulatory Board (AERB) as well as Mammalian cell culture lab.

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Intracerebroventricular drug delivery using stereotaxic apparatus and Cerebrospinal fluid (CSF) tapping/aspiration for biomarker and drug/metabolite analysis.

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Preclinical R & D.

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