Government Aided Pharmacy College Permanently Affiliated To University Of Mumbai, Approved By AICTE DTE And PCI, NBA Accreditation For 2008-2013,

Only Pharmacy Institute in INDIA rated as Best Industry Linked under Mentor category by AICTE-CII

MISSION

To educate and train students in the knowledge and practice of pharmaceutical sciences and to contribute to improvement of health of the society, through education and research programs.

VISION

To be a leader in Pharmacy Education, Pharmacy Training, and Research in Pharmaceutical Sciences.

Faculty of Pharmaceutical Chemistry Departments

Name of the Faculty: Dr. Evans C. Coutinho

Designation: Head and Professor, Dept. of Pharmaceutical Chemistry

Email: :evans@bcpindia.org; evanscoutinho@gmail.com

Personal Website: :http://profeccoutinho.net.in

Teaching Fields : Pharmaceutics, physical pharmacy, dispensing pharmacy, Microbiology, Pharmaceutical engineering





Educational Qualifications:

Sr no. Degree University Year of Passing
1) PhD (Tech.) Mumbai University 1989
2) M. Sc. (Tech.) Mumbai University 1986
3) M. Sc. (Tech.) Mumbai University 1986
4) B. Sc. (Tech.) Mumbai University 1984
5) B. Sc. Mumbai University 1981

Awards and Fellowships:(ALL)

Sr no. Award/Fellowship University
1) a. Chairman of the Board of Studies of Pharmacy, University of Mumbai.
b. Member of the Academic Council, University of Mumbai.
c. Member of the Faculty of Technology, University of Mumbai.
d. Member of the Board of University Teaching and Research for the Faculty of Technology, University of Mumbai.
e. Member of the Research and Recognition Committee for the Board of Studies in Pharmacy, University of Mumbai.
f. Member of the Research and Recognition Committee for the Board of Studies in Biophysics, University of Mumbai.
g. Member of the Research and Recognition Committee of SPTM, NMIMS, Vile Parle.
h. Member of the Board of Studies, School of Sciences, NMIMS, Vile Parle.
i. Member of the Research Progress Committee (RPC) for the faculty of Pharmaceutical Sciences/Pharmacy, NIRMA University, Ahmedabad.
j. Member School Board – School of Chemical Sciences and Pharmacy, Central University of Rajasthan
2012- onwards
2) University Grants Commission (UGC) Research Award 1999
3) Resident Scholarship to the 1998 Residential School on Medicinal Chemistry, Drew University, Madison, New Jersey, USA, 1998
4) Career Award for Young Teachers, All India Council of Technical Education, 1995
5) PAMDAL Best Teacher Award for Pharmacy Colleges in Bombay 1993
6) First Rank in Bombay University at the B.Sc. (Tech.) 1984
7) Nominated by the Vice-Chancellor to the Senate and Students Council of Bombay University, 1984
8) The Dr. M. K. Rangnekar Memorial Bronze Medal 1984
9) The Prof. M. L. Khorana Memorial Prize 1984
10) The Prof. J. G. Kane Memorial Prize 1984
11) The Mrs. R. B. Forster Book Prize 1984
12) The Mrs. Soonabhai Dadabhoy Master Scholarship in Pharmaceuticals & Fine Chemicals 1984
13) IDMA - G. P. Nair Award 1984

Recent Publications: (Best Five in last five years)

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) The Effect of Interaction of 2-Amino-8-Hydroxyquinoline on the Conformation and Unfolding Pathway of Physiological Isomers of Human Serum Albumin National Conference on Frontiers in Biotechnology and Bioinformatics (NCFIBB2014) “Macromolecular Interactions in Biology”, D. Y. Patil Vidyapeeth, Navi Mumbai, 30th – 31st January, 2014
2) Curcumin and Kaempferol Prevent Lysozyme fibril Formation by Modulating Aggregation Kinetic Parameters National Conference on Frontiers in Biotechnology and Bioinformatics (NCFIBB2014) “Macromolecular Interactions in Biology”, D. Y. Patil Vidyapeeth, Navi Mumbai, 30th – 31st January, 2014
3) Pharmacophore Mapping Studies To Identify Novel HCV RNA Polymerase Inhibitors Recent Advances Computational Drug Design” 2013, IISc Bangalore 16th – 17th September 2013
4) Developing New leads as Anti-tubercular agents that target novel biological target of Mycobacterium tuberculosis Recent Advances Computational Drug Design” 2013, IISc Bangalore 16th – 17th September 2013
5) Discovery of Novel Molecular Scaffolds For Vasopressin V1b Antagonists Using Pharmacophore Based Virtual Screening Recent Advances Computational Drug Design” 2013, IISc Bangalore 16th – 17th September 2013

Recent Patents:(ALL)

Sr no. Patent Title Patent Number
1) 6-Methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3, 4-tetrahydropyrimidin-2-one derivatives as antitubercular agents 1. WO2011151701A1
2. CN102971301A
3. Indian Pat. Appl. (2012), IN 2010DE01244 A 20120302

Collaborations: (in current year)

Sr no. Title Industry/institute
1) Molecular Modeling studies 1. Centre for Basic Sciences, DAE-UM, Mumbai.
2. Molecular Biophysics, Dept. Of Chemical Sciences, TIFR, Mumbai.
3. University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh.
4. Chemical Research Laboratory, Dept. Of Chemistry, Saurashtra Univ., Rajkot.
5. National Chemical Laboratory, Pune.
6. Dept. Of Pharmaceutics, Chandigarh College of Pharmacy, Mohali, Panjab.

Consultancy Services: (in last five years)

Sr no. Title Industry/institute
1) In silico resistance estimation BASF, Germany

Research Area and interest:

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Pharmaceutical chemistry, Computer aided drug design, Advances in NMR methodology.


Expertise and instrumental/research facilities you can provide to interested parties:

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Computer aided drug design, homology modelling, docking, pharmacophore modelling, QSAR, molecular dynamics, quantum mechanics

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synthesis of NCEs

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Identification and dynamics of peptides/proteins using multinuclear 1H, 13C and 15N, 1D and 2D NMR methodologies.

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Name of the Faculty: Dr. Krishna Ramalingam Iyer

Designation: : Professor of Pharmaceutical Chemistry

Email: :krishna.iyer@bcp.edu.in

Teaching Fields : Pharmaceutical chemistry, basic biotechnology, pharmacokinetics, basic and advanced biochemistry, drug metabolism





Educational Qualifications:

Sr no. Degree University Year of Passing
1) Ph. D. Minnesota (USA) 1992
2) M. Pharm. Mumbai University 1987
3) B. Pharm. Mumbai University 1985

Awards and Fellowships:(ALL)

Sr no. Award/Fellowship University
1) Best paper award Kadam RS and Iyer KR, Isolation of different animal liver xanthine oxidase containingfractions and determination of kinetic parameters for xanthine. Indian J. Pharm. Sci., 69(1), 41-45, 2007, in the field of Pharmacology and Clinical Pharmacology 2010
2) Assistant Editor - Indian Journal of Pharmaceutical Sciences 2001-present
3) Co-editor - Asian Chemistry Letters Vol. 5(2), 2001, Special Issue on Drug discovery and development 2001
4) 1996 James R. Gillette Best Paper Award in drug metabolism, among all the articles in the 1996 issues of Drug Metabolism and Disposition. 1997
5) Publication entitled "Selectively deuterated warfarin....." selected for the 1996 James R. Gillette Best Paper Award in drug metabolism, among all the articles in the 1996 issues of Drug Metabolism and Disposition. 1996
6) Best Poster Award at the 5th North American ISSX meeting, Tucson, Arizona, USA 1993
7) University of Minnesota President's Student Leadership and Service Award 1991
8) Elected to Who's Who among Students in American Colleges and Universities 1984

Recent Publications: (Best Five in last five years)

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) Quantifying ligand-receptor interactions for gorge spanning acetylcholinesterase inhibitors for the treatment of alzheimer's disease Journal of biomolecular structure & dynamics, 2014, 1-69.
2) Parallel Combinatorial Synthesis and In Vitro Evaluation of Ester and Amide Prodrugs of Flurbiprofen, Ibuprofen and Ketoprofen. Indian J.Pharm. Educ. Res. 2009 43(2)
3) Evaluation of cytochrome P450 2D6 phenotyping in healthy adult Western Indians. Indian J Pharmacol., 46, 266-269, 2014.
4) Assessment of rat hepatic cytochromeP450 induction and inhibition potential of chlorogenic acid. Indian J. Pharm. Edu. Res., 45(1), 32-39, 2011.
5) The significance and determination of plasma protein binding. Encyclopedia of Drug Metabolism and Interactions, 6-Volume Set, First Edition. Lyubimov AV Ed., John Wiley and Sons, Inc., USA, Chapter 12, pp 1-18, 2014

Awards and Honours

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) RP-HPLC method for the estimation of GST activities in different animal hepatic fractions: Comparison with traditional UV method. University of Mumbai’s Avishkar Research Convention 2013-2014, Mumbai, India, Jan 6 & 8, 2014.
2) Effect of commonly used organic solvents of enzyme kinetic parameters of cytochrome P450 mediated reactions in rat liver microsomes, Fifth International symposium on “Drug Metabolism and Pharmacokinetics Symposium: Applications Toward Drug Discovery and Development”, held at NIPER, Mohali, India, March 8-9, 2013.
3) Comparison of UV spectrophotmetric and RP-HPLC method for estimation of GST activities in animal hepatic subcellular fractions Fifth International symposium on “Drug Metabolism and Pharmacokinetics Symposium: Applications Toward Drug Discovery and Development”, held at NIPER, Mohali, India, March 8-9, 2013.
4) Evaluation of the activity of cytochrome P450 2D6 (CYP2D6) in normal, healthy, western Indian population by phenotyping 5th International Conference of South Asian Chapter of American College of Clinical Pharmacy, Mumbai, India, August 26-28, 2011.
5) Evaluation of cocktail approach for phenotyping of CYP2A6, CYP2C9 and N-acetyl transferase activities. /62nd Indian Pharmaceutical Congress, Manipal, India, December 2010.

Collaborations: (in current year)

Sr no. Title Industry/institute
1) Three year of Fellowship for metabolic studies Bristol Mayer Squibb

Research Area and interest:

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Teaching duties include pharmaceutical chemistry, pharmaceutical biotechnology, basic and advanced biochemistry, basic and advanced drug metabolism, and pharmacokinetics. Research interests include mechanistic drug metabolism, evaluation of in vitro drug metabolism methodology, development of in vitro enzyme assays for drug metabolizing enzymes, population phenotyping and genotyping, and drug- drug interaction predictions.

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Name of the Faculty: Dr. Premlata Kuldip Ambre

Designation: : Assistant Professor in Pharmaceutical Chemistry

Email: :pambre@bcpindia.org

Teaching Fields : Pharmaceutical chemistry, organic chemistry, general chemistry, advanced medicinal chemistry





Educational Qualifications:

Sr no. Degree University Year of Passing
1) Ph. D. (Tech) Mumbai University 2001
2) M. Pharm. Mumbai University 1997
3) B. Pharm. SNDT 1995

Recent Publications: (Best Five in last five years)

Sr no. Paper Title Journal / Year / Vol / Page
1) Antifolate agents against wild and mutant strains of plasmodium falciparum Indian journal of pharmaceutical sciences, 2014, 76, 116-124.
2) Quantifying ligand-receptor interactions for gorge spanning acetylcholinesterase inhibitors for the treatment of alzheimer's disease Journal of biomolecular structure & dynamics, 2014, 1-69.
3) Extracting Structural requirements for activity of GPR119 agonists: An Hologram Quantitative Structure Activity Relationship (HQSAR) study Canadian Journal of Chemistry, 2014, Accepted
4) Design, synthesis, and evaluation of 4-(substituted) phenyl-2-thioxo-3, 4-dihydro-1H-chromino [4, 3-d] pyrimidin-5-one and 4-(substituted) phenyl-3, 4-dihydro-1H-chromino [4, 3-d] pyrimidine-2, 5-dione analogs as antitubercular agents Medicinal Chemistry Research 2014, 23 (5), 2564-2575
5) Identification of new checkpoint kinase-1 (Chk1) inhibitors by docking, 3D-QSAR, and pharmacophore-modeling methods Canadian Journal of Chemistry 2012, 90 (8), 675-692

Recent Publications: (Best Five in last five years)

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) Design and Synthesis of Thermo responsive Polymers for Water Purification and Pharmaceutical Applications Avishkar-2014, Mumbai at Mumbai University on 6th Jan2014
2) Developing new leads as antitubercular agents that target novel biological target of Mycobacterium tuberculosis Recent Advances in Computational Drug Design organized by Schrodinger at Indian Institute of Science, Banglore on 16th and 17th September 2013
3) Gastroprotective activity of Fenugreek seeds: An in vitro, in vivo and in silico approach 45th Annual Conference of Indian Pharmacological Society and International Conference on “Navigating Pharmacology towards Safe and Effective Therapy.”, Nagpur 5th – 7th January 2013
4) Potential Anti-tubercular Hits: Design, Synthesis and Evaluation of 2,5 di-substituted benzimidazoles National Symposium on “Frontiers of Biophysics, Biotechnology and Bioinformatics” & 37th Annual Meeting of Indian Biophysical Society (IBS), Mumbai 13th – 16th January, 2013
5) Discovery of novel leads as dual acting inhibitors of acetylcholinesterase using pharmacophore modeling, docking consensus and 3D-QSAR studies for Alzheimer’s disease.” 3rd World Congress on Biotechnology, Hyderabad, 13th – 15th September, 2012

Collaborations: (in current year)

Sr no. Title Industry/institute
1) Evaluation of antitubercular agents National Chemical Laboratory, Pune
2) Design and Synthesis of Thermo responsive Polymers for Water Purification and Pharmaceutical Applications Faculty of Science, Engineering and Computing. Kingston University, London

Research Area and interest:

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Rational design and synthesis of novel chemotherapeutic agents, combinatorial chemistry, 3D-QSAR, chromatographic separation of mixtures


Expertise and instrumental/research facilities you can provide to interested parties:

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Bulk synthesis of drugs and impurities

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Bulk separation of components from mixtures using flash chromatography

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Parallel synthesis for combinatorial chemistry

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Microwave assisted synthesis of NCEs

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Name of the Faculty: Mr. Abhijeet T. Dalvvi

Designation: : Assitant Professor of Pharmaceutical Chemistry

Email: :: dalvvi@bcpindia.org

Teaching Fields : General Chemistry, Organic Chemistry, Pharmaceutical Analysis, Biochemistry





Educational Qualifications:

Sr no. Degree University Year of Passing
1) M. Pharm. Shivaji University, Kolhapur 2005
2) B. Pharm. Pune University 2002

Research Area and interest:

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Pharmacology of medicinal plants, Synthesis of NCEs

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