Pharmaceutical Chemistry

Ms. Khushboo Begwani

Name of the Faculty: Ms. Khushboo Begwani

Designation: Assistant Professor

Qualification: Ph. D. (pursuing)

Teaching Experience (Years): 4 years

Research Experience (Years): 8

LinkedInhttps://www.linkedin.com/in/khushboo-begwani-73a2b1106

Email: khushboo.begwani@bcp.edu.in,kvbegwani93@gmail.com

Google scholar: https://scholar.google.com/citations?user=HRPdhqoAAAAJ&hl=en

ResearchGate / Academia profile: https://www.researchgate.net/profile/Khushboo-Begwani-2?ev=hdr_xprf

Orchid: https://orcid.org/0000-0003-2029-1661

Specialization / Area of Expertise: Design, synthesis of novel drug conjugates; computer-aided drug design; Herbal formulations

Professional Overview

Ms. Khushboo Vijay Begwani, M. Pharm (Pharm. Chem.) is an Assistant Professor at the Bombay College of Pharmacy (Autonomous), Mumbai, specialising in pharmaceutical chemistry and computational drug discovery. Her work bridges ligand and structure-based design, molecular docking/MD, and bench-side validation (anti-proliferative, anti-migratory, anti-angiogenic assays), with a disease focus on breast cancer (MCF-7) and RTK-driven malignancies (c-Met, VEGFR-2, EGFR/CDK2).

Academic and Administrative Leadership

• Current appointment: Assistant Professor, Bombay College of Pharmacy (since May 2025). Responsibilities include UG/PG teaching in Pharmaceutical Chemistry, and curriculum delivery.
• Prior roles: Assistant Professor at Prin. K. M. Kundnani College of Pharmacy (Nov 2021–Jun 2024); Assistant Professor at Dnyan Ganga College of Pharmacy (Oct 2024–Apr 2025).
• Course portfolio (illustrative): Pharmaceutical Inorganic Chemistry, Pharmaceutical/Organic Chemistry I–II (theory & practical), and M.Pharm lab modules.
• Departmental activities: Coordinating national workshops and academic outreach (e.g., Biostatistics & DoE with JMP® under IQAC, Dec 2025).

Research Interests and Contributions

• Computational & medicinal chemistry: Choosing biologically relevant protein conformers for docking (e.g., c-Met 3ZXZ), enrichment-based validation, and hybrid scaffolds (benzamide-chalcones; cinnamamide-chalcones).
• Mechanistic pharmacology: RTK-targeted inhibitors (c-Met, VEGFR-2) and dual-target strategies (e.g., c-Met/COX-2) supported by in-vitro SRB, colony formation, wound-healing, and anti-angiogenesis assays.
• Translational orientation: Comparative pharmacophore modelling with kinase flexibility; BSA-binding and selectivity profiling.

Research Grants and Collaborations

• Inter-institutional collaboration: Multi-author research with medicinal chemists, pharmacologists, and reproductive biology experts for dual-target c-Met/COX-2 studies and wet-lab validation.
• Departmental/industry linkage: Participation in academic–industry interfaces (e.g., JB Chemicals industrial visit coordination) and method-development skill-building (HPLC/GC/KF) from early training stints.

Societal Impact and Community Engagement

• Student enrichment & employability: Organising industrial exposure and cultural/academic events that strengthen soft-skills and industry readiness.
• Open science practices: Preprints/ORCID curation and public dissemination of docking/assay methodologies to accelerate reproducibility and adoption in teaching labs.
• Mentoring & outreach: Active LinkedIn presence to amplify opportunities and foster a network for trainees and alumni.

Innovation, Patents, and Digital Health Initiatives

• Patent: Published a patent “A GEL FORMULATION COMPRISING METHOTREXATE AND HIBISCUS ROSA SINENSIS EXTRACT AND PREPARATION METHOD THEREOF” date of filling 07/09/2023.
• Digital discovery: Conformer selection & virtual screening pipelines for c-Met type-1 inhibitors with ROC/BEDROC/EF analysis, enabling robust in-silico triage and reducing false negatives prior to synthesis.
• Translational medicinal chemistry: Molecular hybridisation strategies (benzamide-chalcones) aimed at multi-pathway modulation (c-Met, COX-2) and anti-angiogenesis profiling.

Mentorship, Awards, and Recognitions

• Mentorship: UG/PG lab supervision and research guidance in heterocycle design, anti-proliferative testing, and CADD; departmental teaching dossier reflects a broad chemistry load across B. Pharm and M. Pharm practicals.
• Recognitions & invited activities: Conference/poster participation and institutional coordination roles (e.g., Research Scholar Meet presentation on c-Met inhibitors; national IQAC workshop co-ordination).
• Student Aryan Walekar Secured Bronze medal (Final Round) in UG level presentation, Category 6- Medicine and Pharmacy at Aavishkar 2026.
• First place secured one day National Seminar on "Innovation-Optimization: A New Paradigm for the Development of Pharmaceuticals" organized by Principal K. M. Kundnani College of Pharmacy's Institute Innovation Council (IIC) in Collaboration with Association of Pharmaceutical Teachers of India on 25th March 2023.

Professional Memberships and Editorial Roles

• Professional community: Active on scholarly platforms (Google Scholar, ORCID) and college networks; departmental rosters list teaching and research roles in Pharmaceutical Chemistry.

Recent Publications: (Best Five in last five years)