Department of Pharmacognosy and Phytochemistry
Dr. Alka Pravin Mukne
Name of the Faculty: Dr. Alka Pravin Mukne
Designation: Associate Professor of Pharmacognosy and Phytochemistry
Email: alka.mukne@gmail.com, alka.mukne@bcp.edu.in
Teaching Fields : Pharmacognosy and Phytochemistry.
Professional Overview
Dr. Alka Mukne is presently Head, Department of Pharmacognosy & Phytochemistry at Bombay College of Pharmacy. An accomplished pharmaceutical scientist with over 3 decades of rich experience in pharmaceutical teaching and research, Dr. Mukne has successfully guided M. Pharm. and 4 Ph. D. students. Her research students are all well - placed in industry and academia, both on the national as well as international landscape.
Dr. Alka Mukne has been invited as Member of the Pharmacy Council of India (PCI) Syllabus Committee for undergraduate & postgraduate pharmacy & has played an active role in contributing to the updation & revision of BPharm & MPharm syllabus that was implemented in pharmacy colleges across the country. As Member of Expert Working Group, Indian Pharmacopoeia Commission, she has actively contributed to revisions in monographs of Indian Pharmacopoeia (IP).
As a committed professional, with a strong ethos of giving back to the profession, Dr. Mukne has been actively involved in professional associations & societies in senior leadership roles, including Indian Pharmaceutical Association (IPA), Society for Ethnopharmacology (SFE) and Society for Pediatric Medicines & Healthcare Initiatives (PMHI).
Educational Qualifications:
| Sr. No. | Degree | University | Year of Passing |
|---|---|---|---|
| 1 | PhD (Tech.) | Mumbai University | 2005 |
| 2 | M. Pharm | Mumbai University | 1993 |
| 3 | B. Pharm | Mumbai University | 1991 |
Awards and Fellowships:(ALL)
| Sr. No. | Award/Fellowship | University |
|---|---|---|
| 1 | Received 2016 IPA fellowship awarded by the Indian Pharmaceutical Association | 2016 |
| 2 | Editor, Pharma Times | 2008 - to date |
| 3 | Marquis's Who's Who in Science and Engineering, 10th edition, biographical listing | 2008 |
| 3 | Marquis's Who's Who in Science and Engineering, 10th edition, biographical listing | 2008 |
| 3 | Outstanding Achievement Award by the Indian Pharmaceutical Association | 2006 |
Recent Publications: (Best Five in last five years)
| Sr. No. | Paper Title(Best Five in last five years) | Jounal Details |
|---|---|---|
| 1 | Assessment of chemical stability of constituents in thiosulfinate derivative-rich extract of garlic by a validated HPTLC method | Indian Journal of Pharmaceutical Sciences. 2017; 79(3): 438-50 |
| 2 | Allium sativum constituents exhibit anti-tubercular activity in vitro and in RAW 264.7 mouse macrophage cells infected with Mycobacterium tuberculosis H37Rv | Pharmacognosy Magazine. 2017; 13(2): S209 |
| 3 | Acute toxicity studies of nano-formulations of Glycyrrhiza glabra extract in swiss albino mice | WJPPS, 2017. 6(6): 820-829 |
| 4 | Development and validation of HPLC and HPTLC methods for estimation of glabridin in extracts of Glycyrrhiza glabra | J AOAC Int, 2016. 99: 374-379 |
| 5 | Validated HPTLC Method for Simultaneous Quantification of Isoniazid, Rifampicin and Glabridin | J. Pharm. BioMed. Sci. 2016. 6(7): 453-459 |
Recent Patents:(ALL)
| Sr. No. | Patent Title | Patent Number |
|---|---|---|
| 1 | Gastroretentive systems & novel pharmaceutical compositions thereof | Indian Patent No. 234801 (1301/MUM/2003) |
Recent Presentation:Best Five in last five years
| Sr.No. | Title | Conference Details |
|---|---|---|
| 1 | Development and validation of HPTLC method for simultaneous quantification of isoniazid, rifampicin and glabridin | 68th Indian Pharmaceutical Congress held at Vishakhapatnam in December 2016 |
| 2 | Design, optimization and in vitro evaluation of solid lipid nanoparticles of Berberis aristata for anti-tubercular activity | 68th Indian Pharmaceutical Congress held at Vishakhapatnam in December 2016 |
| 3 | Anti-tubercular activity of acetone extract of Glycyrrhiza glabra Linn. | 67th Indian Pharmaceutical Congress held at Mysore in December 2015 |
| 4 | Isolation of stable organosulfur compounds from Garlic: Evaluation and formulation as effective anti-mycobacterial agents | 63rd Indian Pharmaceutical Congress, Bengaluru, from December 16th - 18th, 2011. |
| 5 | Extraction, evaluation and formulation studies of volatile fractions of Allium sativum as novel antitubercular agents | 63rd Indian Pharmaceutical Congress, Bengaluru, from December 16th - 18th, 2011. |
Research Area and interest:
- Standardization of crude drugs and herbal extracts.
- Study of different parameters of extraction of herbal drugs and optimization of conditions of extraction to maximize the yield of extracts.
- Isolation and characterization of phytoconstituents from herbal extracts.
- Solubility manipulations of poorly water-soluble drugs of natural & synthetic origin by complexation with cyclodextrins, use of cosolvents & drug amorphization.
- Evaluation ofAnalytical method development and validation for crude drugs, herbal extracts and herbal formulations by HPLC, HPTLC and other chromatographic & electrophoretic techniques. therapeutic potential of crude drugs and their various extracts. Screening antitubercular and antimicrobial activity, biofilm inhibitory activity, of medicinal compounds, herbal extracts and phytomolecules.
- Development & evaluation of conventional formulations and Novel Drug Delivery Systems of herbal extracts and fractions.
- Stability studies and shelf life study of herbal formulations.
- Phytochemical analysis of plants and herbal products, pharmacological screening of plant and plant products.
- Formulation development studies of herbal extracts & isolates including conventional and novel drug delivery systems.
- Solubility manipulations of poorly water-soluble drugs of natural & synthetic origin by complexation with cyclodextrins, use of cosolvents & drug amorphization.
- Stability studies & shelf life estimation of herbal formulations.
Research Output
- 1 Indian Patent granted in 2009.
- 19 papers published in Science Citation Index (SCI) - listed, peer-reviewed research journals.
- 5 book chapters in books published by Elsevier, CRC Press, Francis & Taylor, Studium Press, LLC USA & Springer Nature, Singapore Pvt. Ltd.
- Around 150 editorials contributed, that address issues concerning the pharmaceutical regulatory, academia and industry sectors, every month in Pharma Times, since 2010 to 2024.
- 15 research papers presented in international & national conferences.
Research Grants and Collaboration
Dr. Alka Mukne received total research funding over INR 100, 00,000/- from industry and Government of India research funding agencies including.
- Council of Scientific & Industrial Research (CSIR)
- Department of Biotechnology (DBT)
- Department of Atomic Energy – Board for Research in Nuclear Sciences (DAE -BRNS)
- Society for Research & Initiatives for Sustainable Technologies & Institutions- Biotechnology Industry Research Assistance Council (SRISTI-BIRAC)
- Amrut Mody Research Foundation (AMRF)
- All India Council of Technical Education – Research Promotion Scheme (AICTE – RPS)
- University of Mumbai - Minor Research Grant
Expertise and instrumental/research facilities you can provide to interested parties:
- Extraction of drug compounds from mixtures and plant parts
- Separation of mixtures using chromatographic techniques.
- Lyophilization of extracts, biphasic liquid & semisolid systems and novel drug delivery systems
- Developing conventional & novel drug delivery systems of phytoextracts & phytoisolates.
- HPTLC analysis of drugs, extracts and formulations.
- Analytical method development & validation studies for APIs, formulations & cosmetics, with special interest in those of herbal origin.
Professional Assignments
Indian Pharmaceutical Association (IPA)
2010 - Present
As National Hon. Treasurer, IPA, since 2024, Dr. Alka Mukne has been involved in managing the financial affairs of IPA. As Member, Board of Trustees of IPA since 2010 to date, have been involved in senior policy decision making of the Association and ensuring that the objectives of the Association are met. During this period, she has functioned as Scientific Convener & Member of Scientific Committee of various IPA events viz. IPA Conventions, IPA conferences with American Association of Pharmaceutical Scientists (AAPS), International Pharmaceutical Federation (FIP), Indian Pharmacopoeia Commission (IPC), The Academy of Pharmaceutical Sciences & Technology, Japan (APSTJ) & European Directorate of Quality of Medicines (EDQM).
Pharma Times, Official Publication of IPA
2010 - 2024
As Hon. Editor, Pharma Times from 2010 to 2024, had been responsible for editing, publishing and printing around 13,000 copies of Pharma Times every month, that are sent complimentary to all IPA members and IPA affiliates including FIP, AAPS, CPA, FAPA and WHO. Celebrated the completion of 50 years of Pharma Times, by organizing a commemorative conclave with enthusiastic participation from top regulators & industry.
Pharmacy Council of India (PCI)
2016 - 2022
As Member of the B. Pharm. & M. Pharm. Syllabus Committee of PCI, was responsible for framing & finalizing the syllabus for B. Pharm. Course, that is being implemented by pharmacy colleges in India.
Indian Pharmacopoeia Commission (IPC)
2016 - 2022
As Member of the B. Pharm. & M. Pharm. Syllabus Committee of PCI, was responsible for framing & finalizing the syllabus for B. Pharm. Course, that is being implemented by pharmacy colleges in India.
Indian Pharmacopoeia Commission (IPC)
2017 - 2022
As Member, Expert Working Group – General Chapters, Indian Pharmacopoeia, have been involved in revising and defining pharmacopoeial standards in General Chapters. For reasons of confidentiality, more details cannot be shared here.
Society for Ethnopharmacology (SFE)
2017 - present
As Founder Co-ordinator, Mumbai Chapter of SFE, setup the Mumbai Chapter of the Society in 2017 and since then am responsible for furthering the objectives of the Society by ensuring growth in member base and organizing seminars and workshops that help disseminate knowledge in the area of natural product research. The maiden seminar of the Mumbai Chapter was organized in December 2018, in collaboration with HADSA, IDMA & AFSTI.
Pediatric Medicine & Healthcare Initiative (PMHI)
2021 - present
Founder Member & Founder Hon. Treasurer of PMHI, a non profit organization formed to help identify the issues in developing pediatric formulation, & registered as a Society in 2021.
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